Genetic analysis of the association between alcohol, copyright, and opiate addiction and variable number tandem repeat (VNTR) polymorphisms in monoamine oxidase B (MAOB) and serotonergic 5-hydroxytryptamine (serotonin) receptor 1B and 2C (HTR1B 21 and HTR2C) pathway genes was performed in a sample of 302 polyconsumers.Our genetic association analysis revealed a significant association between a 184 base Panel Hardware pair (bp) VNTR polymorphism in the MAOB gene and addiction to copyright and opiates.This work highlights new genetic marker associations in copyright and opiate polyconsumer addictions.
These data help to clarify and quantify the complex role of genetics in addictive disorders, as well as their future Missing Link contribution to the prevention (genetic counselling), diagnosis (genetic diagnosis of vulnerability), and treatment (pharmacogenomics) of these disorders.